SCHEMBL22722643

SCHEMBL22722643

CNC(=O)OCCN1C(=O)N(CCOC(=O)NC)C(C)(C)C1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 3/20 0.39
CHRNB2 P17787 2/20 0.37
CHRNA4 P43681 2/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CYP2D6 P10635 1/20 0.37
CHRM1 P11229 1/20 0.37
NFKB1 P19838 1/20 0.37
CHRM3 P20309 1/20 0.37
MAPK1 P28482 1/20 0.37
CHRNA7 P36544 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
APEX1 P27695 1/20 0.36
EPHX1 P07099 1/20 0.36
KDM4E B2RXH2 2/20 0.34
GLA P06280 1/20 0.34
MMP3 P08254 4/20 0.32
MMP2 P08253 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11332808 0.83 ALDH1A1 (0.41) PLA2G7CHRNB2CHRNA4CHRM2CHRM4
SCHEMBL10878204 0.79 PLA2G7 (0.42) PLA2G7APEX1RAB9A
SCHEMBL5808485 0.78 TSHR (0.42) PLA2G7RAB9A
SCHEMBL11554169 0.77 PLA2G7 (0.40) PLA2G7MAPK1APEX1RAB9A
SCHEMBL11054800 0.75 PLA2G7 (0.36) PLA2G7
SCHEMBL11527032 0.74 PLA2G7 (0.41) PLA2G7MAPK1SMN1; SMN2LMNAMMP3
SCHEMBL11430119 0.73 PLA2G7 (0.40) PLA2G7MAPK1SMN1; SMN2LMNAMMP3
SCHEMBL10036477 0.71 MGLL (0.50) CHRNB2CHRNA4CHRM2CHRM4CHRM5
SCHEMBL11641541 0.70 PLA2G7 (0.34) PLA2G7MAPK1SMN1; SMN2RAB9AHTR1A
SCHEMBL11641539 0.69 PLA2G4B (0.41) PLA2G7MAPK1SMN1; SMN2LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10851264-B2 Optical fiber coating composition NUFERN (US) 2020-12-01 US disclosed