Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054827 | 0.82 | ALDH1A1 (0.39) | THRBALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL42893 | 0.82 | HCAR2 (0.51) | THRBHCAR2ESR1ESR2ALDH1A1 | |
| Ethylene Glycol SCHEMBL6490846 | 0.80 | HCAR2 (0.47) | THRBHCAR2ESR1ESR2ALDH1A1 | |
| Methane SCHEMBL4468486 | 0.80 | HCAR2 (0.50) | THRBHCAR2ESR1ESR2ALDH1A1 | |
| SCHEMBL7937982 | 0.79 | HCAR2 (0.46) | THRBHCAR2ESR1ESR2ALDH1A1 | |
| SCHEMBL27973892 | 0.79 | HCAR2 (0.49) | THRBHCAR2ESR1ESR2ALDH1A1 | |
| Methacrylic Acid SCHEMBL8131805 | 0.79 | HCAR2 (0.49) | THRBHCAR2ESR1ESR2ALDH1A1 | |
| SCHEMBL268177 | 0.79 | THRB (0.40) | THRBALDH1A1TSHR | |
| SCHEMBL150510 | 0.76 | LMNA (0.49) | THRBHCAR2ESR1ESR2ALDH1A1 | |
| SCHEMBL7873904 | 0.76 | THRB (0.40) | THRBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000034804-A1 | HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-06-15 | — | — | WO | disclosed |