Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10776023 | 0.77 | TP53 (0.41) | TP53PSIP1TDP1TSHRLMNA | |
| SCHEMBL2849047 | 0.74 | TDP1 (0.42) | TP53PSIP1TDP1TSHRPCSK9 | |
| SCHEMBL20953824 | 0.69 | TP53 (0.39) | TP53PSIP1TSHRLMNAALOX12 | |
| SCHEMBL11054885 | 0.69 | CALM1 (0.43) | TP53TDP1TSHRALOX12CALM1 | |
| SCHEMBL9747193 | 0.67 | TRPA1 (0.31) | TSHRALDH1A1MAPK1 | |
| SCHEMBL7055454 | 0.65 | — | — | |
| SCHEMBL10551724 | 0.65 | TSHR (0.39) | TP53TDP1TSHRLMNAALOX12 | |
| SCHEMBL20441 | 0.63 | ALDH1A1 (0.40) | TDP1TSHRLMNAALOX12ACHE | |
| Biphenyl SCHEMBL9116003 | 0.63 | ALDH1A1 (0.60) | TP53TDP1ATMALDH1A1MEN1 | |
| SCHEMBL29097667 | 0.63 | TSHR (0.37) | TP53TDP1TSHRLMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0568289-A2 | Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors | Eisai Co., Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |