Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | CASP1 | P29466 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | CASP7 | P55210 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850407 | 1.00 | ALDH1A1 (0.69) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL29398835 | 1.00 | ALDH1A1 (0.69) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL9976810 | 0.94 | DRD2 (0.63) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| Laurotetanine SCHEMBL31300083 | 0.89 | DRD2 (0.74) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| Laurotetanine SCHEMBL905125 | 0.89 | DRD2 (0.74) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| Laurotetanine SCHEMBL905065 | 0.89 | DRD2 (0.74) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| Norboldine SCHEMBL14367906 | 0.88 | DRD1 (0.71) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| Norboldine SCHEMBL29402012 | 0.88 | DRD1 (0.71) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| Norboldine SCHEMBL29886755 | 0.88 | DRD1 (0.71) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| Norboldine SCHEMBL27987614 | 0.88 | DRD1 (0.71) | ALDH1A1KDM4EHPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461895-A | FOR COMBATTING COLDS AND ALLERGIES | WARNER-LAMBERT COMPANY (US) | 1984-07-24 | — | — | US | disclosed |
| EP-0064685-A1 | Dibenzo(de,g)quinolines, processes for their preparation and pharmaceutical preparations containing them | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1982-11-17 | — | — | EP | disclosed |