Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.72 |
| ▸ | DRD1 | P21728 | 5/20 | 0.68 |
| ▸ | HTR2C | P28335 | 2/20 | 0.68 |
| ▸ | PTPRCAP | Q14761 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.62 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.62 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Laurotetanine SCHEMBL905065 | 1.00 | DRD2 (0.74) | DRD2ALDH1A1HPGDKDM4EHSD17B10 | |
| Laurotetanine SCHEMBL31300083 | 1.00 | DRD2 (0.74) | DRD2ALDH1A1HPGDKDM4EHSD17B10 | |
| Norboldine SCHEMBL29402012 | 0.94 | DRD1 (0.71) | DRD2ALDH1A1HPGDKDM4EHSD17B10 | |
| Norboldine SCHEMBL27987614 | 0.94 | DRD1 (0.71) | DRD2ALDH1A1HPGDKDM4EHSD17B10 | |
| Norboldine SCHEMBL14367906 | 0.94 | DRD1 (0.71) | DRD2ALDH1A1HPGDKDM4EHSD17B10 | |
| Norboldine SCHEMBL29886755 | 0.94 | DRD1 (0.71) | DRD2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL30828734 | 0.93 | DRD1 (0.70) | DRD2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL14259791 | 0.92 | DRD1 (0.71) | DRD2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL9976807 | 0.92 | DRD1 (0.76) | DRD2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL14259787 | 0.91 | ALDH1A1 (0.65) | DRD2ALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012043900-A1 | PHARMACEUTICAL COMPOSITION CONTAINING QUINOLINE DERIVATIVE | 동아제약주식회사 (KR) | 2012-04-05 | — | — | WO | disclosed |