Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14901820 | 0.87 | SNCA (0.30) | — | |
| SCHEMBL1105648 | 0.86 | ALDH1A1 (0.33) | KDM4ESMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL1105654 | 0.85 | ALDH1A1 (0.32) | KDM4ESMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL1105649 | 0.83 | KMT2A (0.32) | KDM4ESMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL13746379 | 0.83 | ALDH1A1 (0.31) | KDM4ESMN1; SMN2ALDH1A1HPGDMCOLN3 | |
| SCHEMBL1105646 | 0.82 | RAB9A (0.31) | KDM4ESMN1; SMN2ALDH1A1HPGDLMNA | |
| SCHEMBL13686240 | 0.81 | ALDH1A1 (0.41) | KDM4ESMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL13223484 | 0.80 | ADRB2 (0.41) | KDM4ESMN1; SMN2ALDH1A1NPSR1MAPT | |
| SCHEMBL12302006 | 0.78 | ADRB2 (0.31) | SMN1; SMN2MAPTPOLB | |
| SCHEMBL13686241 | 0.78 | MAPT (0.35) | KDM4ESMN1; SMN2TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846952-B2 | Detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes | ENZO LIFE SCIENCES, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-8759526-B2 | Dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes—useful or detection or quantification of desirable target molecules | ENZO LIFE SCIENCES, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-8574881-B2 | Compositions useful for detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes | ENZO LIFE SCIENCES, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| US-8389729-B2 | Methods for detecting the presence, location or quantity of targets using novel dyes | ENZO LIFE SCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-20130045480-A1 | Novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - useful or detection or quantification of desirable target molecules | ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) | 2013-02-21 | — | — | US | disclosed |
| US-8153802-B2 | Dyes linked to target molecules, oligonucleotides or polynucleotides comprising dye molecules, composite dyes and other compositions useful for detecting or quantifying desirable target molecules | ENZO LIFE SCIENCES, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| US-20120040430-A1 | Compositions useful for detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes | ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| US-20100228008-A1 | Dyes linked to target molecules, oligonucleotides or polynucleotides comprising dye molecules, composite dyes and other compositions useful for detecting or quantifying desirable target molecules | ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-20100041020-A1 | Methods for detecting the presence, location or quantity of targets using novel dyes | ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) | 2010-02-18 | — | — | US | disclosed |
| US-7569695-B2 | Cyanine dyes substituted by electrophilic groups and/or nucleophilic groups including merocyanine, methine, oxazoline, oxonol, selenazole fluorescent, imidazoline, quinoline, indole, reactive and cationic dyes; labeling reagents for proteins and nucleic acids; genetic probes; amplification; hybridization | ENZO LIFE SCIENCES, INC. (US) | 2009-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045480-A1 | Novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - useful or detection or quantification of desirable target molecules | ANXA5, DCLRE1B, ANXA4 | KDM4E 4658/4885SMN1; SMN2 3378/4885TSHR 3492/4885 |
| US-20100228008-A1 | Dyes linked to target molecules, oligonucleotides or polynucleotides comprising dye molecules, composite dyes and other compositions useful for detecting or quantifying desirable target molecules | ANXA5, POLRMT, DCLRE1B | KDM4E 4703/4885SMN1; SMN2 4048/4885TSHR 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.