Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 13/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055326 | 0.74 | MEN1 (0.66) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11056923 | 0.69 | KMT2A (0.64) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL22639884 | 0.69 | LMNA (0.70) | KMT2AMEN1ABCB1LDHAALDH1A1 | |
| SCHEMBL22639882 | 0.69 | LMNA (0.70) | KMT2AMEN1ABCB1LDHAALDH1A1 | |
| SCHEMBL11065237 | 0.69 | MEN1 (0.81) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11061130 | 0.68 | KMT2A (0.79) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL4903750 | 0.64 | HTR1A (0.75) | — | |
| SCHEMBL22639821 | 0.64 | ABCB1 (0.67) | KMT2AMEN1ABCB1LDHAALDH1A1 | |
| SCHEMBL16392428 | 0.64 | ABCB1 (0.67) | KMT2AMEN1ABCB1LDHAALDH1A1 | |
| SCHEMBL11653579 | 0.62 | LMNA (0.62) | KMT2AMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446323-A | Tetra- and hexa-hydropyrrolo(1,2-a)quinoxaline and azaquinoxaline derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-05-01 | — | — | US | claimed |
| US-4446323-A | Tetra- and hexa-hydropyrrolo(1,2-a)quinoxaline and azaquinoxaline derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-05-01 | — | — | US | disclosed |