SCHEMBL11058293

SCHEMBL11058293

FC(F)(F)[SiH](Oc1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
LTA4H P09960 1/20 0.35
ALDH1A1 P00352 1/20 0.32
CA4 P22748 1/20 0.32
KCNA3 P22001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706107 0.78 CA4 (0.37) TSHRLTA4HALDH1A1CA4KCNA3
SCHEMBL1051361 0.75 LTA4H (0.39) TSHRLTA4HALDH1A1CA4KCNA3
SCHEMBL27959345 0.72 MAPK1 (0.32) TSHRALDH1A1
SCHEMBL27545722 0.70 LTA4H (0.39) TSHRLTA4HALDH1A1CA4KCNA3
SCHEMBL1930199 0.69 LTA4H (0.43) TSHRLTA4HALDH1A1CA4KCNA3
SCHEMBL6916437 0.69 LTA4H (0.43) TSHRLTA4HALDH1A1CA4KCNA3
SCHEMBL28156179 0.67 LMNA (0.31)
SCHEMBL6835371 0.67 TSHR (0.38) TSHRALDH1A1CA4
SCHEMBL705308 0.66 LTA4H (0.45) TSHRLTA4HALDH1A1CA4KCNA3
SCHEMBL1052821 0.66 ALDH1A1 (0.41) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4481365-A POSTEMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 1984-11-06 US claimed
US-4481365-A POSTEMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 1984-11-06 US disclosed
US-4481365-A POSTEMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 1984-11-06 US disclosed
US-4481365-A POSTEMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 1984-11-06 US disclosed