Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054404 | 0.88 | HCAR1 (0.46) | HCAR1FGFR1MEN1POLBKMT2A | |
| SCHEMBL11059402 | 0.88 | KMT2A (0.39) | HCAR1L3MBTL1MEN1POLBMAPT | |
| Hydrochloric Acid SCHEMBL11052665 | 0.86 | HCAR1 (0.44) | HCAR1FGFR1MEN1POLBKMT2A | |
| SCHEMBL11057840 | 0.86 | FGFR1 (0.36) | APLNRHCAR1L3MBTL1SMN1; SMN2FGFR1 | |
| SCHEMBL11057854 | 0.82 | HCAR1 (0.41) | HCAR1FGFR1MEN1POLBKMT2A | |
| SCHEMBL11059212 | 0.82 | HCAR1 (0.38) | HCAR1FGFR1MEN1POLBKMT2A | |
| SCHEMBL11054879 | 0.82 | HCAR1 (0.38) | HCAR1FGFR1POLB | |
| SCHEMBL11057681 | 0.82 | APLNR (0.39) | APLNRHCAR1L3MBTL1SMN1; SMN2CYP19A1 | |
| SCHEMBL11054604 | 0.82 | CHRNA7 (0.47) | HCAR1FGFR1MAPK14 | |
| SCHEMBL11050172 | 0.82 | HCAR1 (0.38) | HCAR1FGFR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452980-A | DIARRHEA | WILLIAM H. RORER, INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4246409-A | ANTIDIARRHEAL AGENTS | WILLIAM H. RORER, INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4225315-A | Triazinones from amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-09-30 | — | — | US | disclosed |