Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 3/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10959345 | 0.85 | PLAU (0.41) | POLBNNMTSIRT6 | |
| SCHEMBL11064906 | 0.83 | MAP3K7 (0.32) | LMNA | |
| SCHEMBL11061481 | 0.80 | PLAU (0.33) | — | |
| SCHEMBL11058669 | 0.77 | GPBAR1 (0.33) | NNMTSIRT6 | |
| SCHEMBL10957826 | 0.76 | POLB (0.36) | POLBNNMTDYRK1A | |
| SCHEMBL6114094 | 0.71 | SLC13A5 (0.36) | — | |
| SCHEMBL11060720 | 0.71 | CYP3A4 (0.36) | LMNA | |
| SCHEMBL11058767 | 0.71 | TSHR (0.32) | POLB | |
| SCHEMBL11061001 | 0.71 | MEN1 (0.35) | — | |
| SCHEMBL11059949 | 0.71 | ACACB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434167-A | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-02-28 | — | — | US | disclosed |