Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10602038 | 0.73 | LMNA (0.62) | ALDH1A1LMNACYP2C9CYP2D6CYP2C19 | |
| SCHEMBL11056072 | 0.71 | MAPT (0.48) | ALDH1A1MAPTCYP3A4HSD17B10TP53 | |
| SCHEMBL10599708 | 0.66 | TDP1 (0.54) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL31488632 | 0.65 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TP53CYP2C9POLB | |
| SCHEMBL17622981 | 0.65 | EP300 (0.59) | ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8573533 | 0.64 | LMNA (0.43) | MAPTLMNAPOLBATM | |
| Acetic Acid SCHEMBL10500202 | 0.64 | BACE1 (0.62) | ALDH1A1MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL4216332 | 0.64 | MMP2 (0.62) | ALDH1A1HSD17B10FFAR1FFAR4POLB | |
| Pyrrole SCHEMBL1260091 | 0.63 | SMN1; SMN2 (0.59) | ALDH1A1TP53CYP2C9POLBCYP2D6 | |
| SCHEMBL9449391 | 0.63 | ATM (0.43) | ALDH1A1MAPTHSD17B10POLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486344-A | CARBONYLDIIMIDAZOLE AS LINKING AGENT, IMMUNOASSY | MILES LABORATORIES, INC. (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0123114-A1 | Urea-linked immunogens, antibodies, and preparative method | MILES LABORATORIES, INC. (US) | 1984-10-31 | — | — | EP | disclosed |