Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885560 | 0.85 | SLC7A5 (0.53) | SLC15A1ALDH1A1ALPIPKMPTGS1 | |
| SCHEMBL2152888 | 0.84 | SLC15A1 (0.48) | SLC15A1ALDH1A1PPARGPPARASLC1A5 | |
| SCHEMBL2152892 | 0.84 | SLC15A1 (0.48) | SLC15A1ALDH1A1PPARGPPARASLC1A5 | |
| SCHEMBL10884575 | 0.84 | SLC15A1 (0.46) | SLC15A1ALDH1A1PPARGPPARASLC1A5 | |
| SCHEMBL10889103 | 0.82 | HCAR2 (0.49) | SLC15A1ALDH1A1SLC1A5ALPIPKM | |
| SCHEMBL10887915 | 0.79 | SLC15A1 (0.46) | SLC15A1ALDH1A1PPARGPPARASLC1A5 | |
| SCHEMBL10884376 | 0.79 | PPARG (0.38) | ALDH1A1PPARGPPARASLC7A5HDAC8 | |
| SCHEMBL10885357 | 0.78 | LTA4H (0.60) | PPARGPPARAPTGS1LTA4HLAP3 | |
| SCHEMBL10886482 | 0.77 | LTA4H (0.48) | SLC15A1ALDH1A1PPARGPPARAALPI | |
| SCHEMBL10888743 | 0.76 | ALDH1A1 (0.45) | SLC15A1ALDH1A1LTA4HHCAR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |