Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884575 | 0.89 | SLC15A1 (0.46) | SLC15A1SLC1A5ALDH1A1ALPIPKM | |
| SCHEMBL10885560 | 0.88 | SLC7A5 (0.53) | HCAR2SLC15A1ALDH1A1ALPIPKM | |
| SCHEMBL11060837 | 0.82 | SLC15A1 (0.43) | HCAR2SLC15A1SLC1A5ALDH1A1ALPI | |
| SCHEMBL10887915 | 0.81 | SLC15A1 (0.46) | SLC15A1SLC1A5ALDH1A1ALPIPKM | |
| SCHEMBL10885357 | 0.80 | LTA4H (0.60) | PTGS1 | |
| SCHEMBL10886331 | 0.80 | SLC7A5 (0.51) | HCAR2PNMTKIF11PKMSLC7A5 | |
| SCHEMBL10886482 | 0.79 | LTA4H (0.48) | SLC15A1ALDH1A1ALPIPKMPTGS1 | |
| SCHEMBL10888831 | 0.77 | RAB9A (0.49) | ALDH1A1MMP2 | |
| Dl-Phenylalanine SCHEMBL28419408 | 0.77 | SLC7A5 (0.71) | PNMTKIF11GRIA2ALPIPKM | |
| SCHEMBL10888743 | 0.76 | ALDH1A1 (0.45) | HCAR2SLC15A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |