Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065296 | 0.93 | PDE5A (0.38) | PDE5AHPSEMAPTKDRKMT2A | |
| SCHEMBL11074215 | 0.88 | HPSE (0.39) | PDE5AHPSEMAPTKMT2A | |
| SCHEMBL11071306 | 0.82 | PDE5A (0.40) | PDE5AHPSEMAPTKMT2AHSD17B10 | |
| SCHEMBL11066087 | 0.81 | KMT2A (0.43) | PDE5AHPSEMAPTKMT2A | |
| SCHEMBL11065268 | 0.81 | CYP2C9 (0.44) | PDE5AHPSEMAPTKMT2A | |
| SCHEMBL11076891 | 0.79 | KMT2A (0.44) | HPSEMAPTKMT2A | |
| SCHEMBL11021159 | 0.79 | MAPK10 (0.38) | PDE5A | |
| SCHEMBL7272018 | 0.77 | PDE5A (0.47) | PDE5AKMT2AHSD17B10 | |
| SCHEMBL10742473 | 0.76 | MAPT (0.42) | HPSEMAPTKMT2A | |
| SCHEMBL11071981 | 0.73 | PDE5A (0.41) | PDE5AHPSEMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |