Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285288 | 0.87 | CRHBP (0.44) | ALDH1A1CRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL1574035 | 0.80 | ALDH1A1 (0.71) | ALDH1A1CYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL17671204 | 0.78 | CES2 (0.44) | ALDH1A1CRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL11418300 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CRHBPCRHR2MAPT | |
| SCHEMBL11421960 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CRHBPCRHR2MAPT | |
| SCHEMBL11739758 | 0.76 | MAPT (0.63) | ALDH1A1CYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL10836221 | 0.76 | MEN1 (0.53) | ALDH1A1MAPTKMT2AMEN1USP2 | |
| SCHEMBL9685916 | 0.75 | S100B (0.49) | ALDH1A1CYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL11414890 | 0.74 | CRHBP (0.48) | ALDH1A1CYP3A4CRHBPCRHR2MAPT | |
| SCHEMBL2742811 | 0.74 | ALDH1A1 (0.58) | ALDH1A1CYP3A4MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439513-A | Color photographic light-sensitive material with naphthol redox dye releaser | FUJI PHOTO FILM CO., LTD. (JP) | 1984-03-27 | — | — | US | disclosed |
| US-4189427-A | Azo dyestuffs from benzene diazo component fused to an aliphatic ring and containing two cyano substituents ortho to the azo group | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |