SCHEMBL3285288

SCHEMBL3285288

CC(=O)N(O)c1cccc(N(O)C(C)=O)c1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
GAA P10253 1/20 0.40
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
HSP90AA1 P07900 1/20 0.39
TSHR P16473 3/20 0.37
ALDH1A1 P00352 3/20 0.37
NPSR1 Q6W5P4 1/20 0.36
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
THRB P10828 1/20 0.34
GLA P06280 1/20 0.34
TSPO P30536 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10836221 0.87 MEN1 (0.53) KMT2AMEN1HSP90AA1ALDH1A1LMNA
SCHEMBL11061731 0.87 ALDH1A1 (0.55) CRHBPCRHR2GAAKMT2AMEN1
SCHEMBL6560324 0.86 ALDH1A1 (0.46) CRHBPCRHR2TSHRALDH1A1NPSR1
SCHEMBL17671204 0.86 CES2 (0.44) CRHBPCRHR2GAAKMT2AMEN1
SCHEMBL28785615 0.85 KCNN4 (0.43) GAAKMT2AMEN1ALDH1A1HSD17B10
SCHEMBL29603007 0.85 KCNN4 (0.43) GAAKMT2AMEN1ALDH1A1HSD17B10
SCHEMBL17681587 0.84 CA12 (0.47) GAAKMT2AMEN1TSHRALDH1A1
SCHEMBL440963 0.83 KDM4E (0.48) CRHBPCRHR2KMT2AMEN1TSHR
SCHEMBL1548437 0.82 MTNR1B (0.55) KMT2AMEN1TSHRKDM4EHPGD
SCHEMBL8432404 0.81 LOXL2 (0.46) CRHBPCRHR2TSHRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825294-B2 Multicomponent system for modifying, decomposing or bleaching lignin, or lignin-containing materials and method of using this system CONSORTIUM ELEKTROCHEM IND (DE) 2005-02-09 EP claimed
US-20010018956-A1 Multi-component system for modifying, degrading or bleaching lignin, lignin-containing materials or similar substances and processes for its use CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH 2001-09-06 US claimed
EP-0983334-A1 ENZYMATIC BLEACHING SYSTEM CONTAINING NEW COMPOUNDS FOR INTENSIFYING ENZYMATIC ACTION Call, Krimhild (DE) 2000-03-08 EP claimed
EP-0825294-B1 Multicomponent system for modifying, decomposing or bleaching lignin, or lignin-containing materials and method of using this system CONSORTIUM ELEKTROCHEM IND (DE) 1999-09-15 EP claimed
WO-1999001607-A2 ENZYMATIC OXIDATION SYSTEM WITH NOVEL ENZYMATIC-EFFECT ENHANCING COMPOUNDS CALL, KRIMHILD (DE) 1999-01-14 WO claimed
WO-1998051772-A1 ENZYMATIC BLEACHING SYSTEM CONTAINING NEW COMPOUNDS FOR INTENSIFYING ENZYMATIC ACTION CALL, KRIMHILD (DE) 1998-11-19 WO claimed
EP-0825294-A1 Multicomponent system for modifying, decomposing or bleaching lignin, lignin-containing materials or similar substances and method of using this system Consortium für elektrochemische Industrie GmbH (DE) 1998-02-25 EP claimed
CN-110892065-A Cleaning method 宝洁公司 2020-03-17 CN disclosed
US-7700196-B2 Method for producing carbonyl group-containing organosilicon compounds WACKER CHEMIE AG (DE) 2010-04-20 US disclosed
EP-1685183-B1 METHOD FOR PRODUCING CARBONYL REST-CONTAINING ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2008-01-16 EP disclosed
US-20070129520-A1 High yield of 2-formylethyldimethylsilanol-modified polydimethylsiloxane obtained by the continuous process of oxidizing 3-hydroxypropyldimethylsilanol-modified corresponding polymer using Tempoas an oxidation catalyst and air or oxygen as oxidizer in an aqueous dispersion; industrial scale; low cost WACKER CHEMIE AG (DE) 2007-06-07 US disclosed
US-20060217281-A1 Oxidation system containing a macrocyclic metal complex, the production thereof and its use LANXESS B.V. (NL) 2006-09-28 US disclosed
EP-1606447-A1 OXIDATION SYSTEM CONTAINING A MACROCYCLIC METAL COMPLEX, THE PRODUCTION THEREOF AND ITS USE Lanxess B.V. (NL) 2005-12-21 EP disclosed
EP-0913382-A1 Process for the preparation of aldehydes and ketones Consortium für elektrochemische Industrie GmbH (DE) 1999-05-06 EP disclosed
EP-0905306-A1 Multicomponent system for modifying, decomposing or bleaching lignin or lignin-containing materials and method of using this system Consortium für elektrochemische Industrie GmbH (DE) 1999-03-31 EP disclosed
WO-1999001607-A2 ENZYMATIC OXIDATION SYSTEM WITH NOVEL ENZYMATIC-EFFECT ENHANCING COMPOUNDS CALL, KRIMHILD (DE) 1999-01-14 WO disclosed
EP-0885868-A1 Oxidation-process for the production of aldehydes and ketones in the presence of nitrogen-containing compounds Consortium für elektrochemische Industrie GmbH (DE) 1998-12-23 EP disclosed
EP-0882814-A1 System and process for the electrochemical cleavage of compounds Consortium für elektrochemische Industrie GmbH (DE) 1998-12-09 EP disclosed
WO-1998051772-A1 ENZYMATIC BLEACHING SYSTEM CONTAINING NEW COMPOUNDS FOR INTENSIFYING ENZYMATIC ACTION CALL, KRIMHILD (DE) 1998-11-19 WO disclosed
EP-0825294-A1 Multicomponent system for modifying, decomposing or bleaching lignin, lignin-containing materials or similar substances and method of using this system Consortium für elektrochemische Industrie GmbH (DE) 1998-02-25 EP disclosed