Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037911 | 0.83 | LMNA (0.36) | — | |
| SCHEMBL27541668 | 0.83 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL15383931 | 0.83 | ALDH1A1 (0.34) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27491495 | 0.81 | CXCR4 (0.34) | ALDH1A1 | |
| SCHEMBL11517818 | 0.81 | CHRNB2 (0.37) | ALDH1A1 | |
| SCHEMBL8860894 | 0.77 | LMNA (0.35) | — | |
| SCHEMBL9660551 | 0.76 | — | — | |
| SCHEMBL1116394 | 0.76 | — | — | |
| SCHEMBL2617060 | 0.76 | — | — | |
| SCHEMBL14806842 | 0.75 | L3MBTL1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440779-A | Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents | MERCK & CO., INC. (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0068460-A1 | Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents | MERCK & CO. INC. (US) | 1983-01-05 | — | — | EP | disclosed |
| US-3956363-A | Substituted indenyl acetic acids | MERCK & CO., INC. (US) | 1976-05-11 | — | — | US | disclosed |
| US-3954852-A | Indenylacetic acid compounds | MERCK & CO., INC. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3932498-A | ANTIINFLAMMATORY, ANTIPYRETICS, ANALGESICS | MERCK & CO., INC. (US) | 1976-01-13 | — | — | US | disclosed |