Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10947750 | 0.86 | HSP90AA1 (0.44) | KMT2AMEN1CYP3A4ALDH1A1HSP90AA1 | |
| SCHEMBL10950761 | 0.82 | HSP90AA1 (0.42) | KMT2AMEN1TSHRHSP90AA1 | |
| SCHEMBL10949391 | 0.80 | PTGS1 (0.43) | KMT2AMEN1CYP3A4ALDH1A1KDM4E | |
| Benzamide SCHEMBL10949386 | 0.79 | PTGS1 (0.43) | KMT2AMEN1CYP3A4TSHRHSP90AA1 | |
| SCHEMBL11041424 | 0.77 | HSP90AA1 (0.40) | KMT2AMEN1GAATSHRHSP90AA1 | |
| SCHEMBL9444661 | 0.69 | ERCC1 (0.75) | ERCC1ERCC4KMT2A | |
| SCHEMBL5804315 | 0.68 | ERCC1 (0.70) | ERCC1ERCC4KMT2AMEN1CYP3A4 | |
| SCHEMBL28946362 | 0.68 | ERCC1 (0.70) | ERCC1ERCC4KMT2AMEN1CYP3A4 | |
| SCHEMBL21963902 | 0.68 | TSPO (0.49) | KMT2ATSHRRAB9A | |
| SCHEMBL3692414 | 0.67 | ERCC1 (0.63) | ERCC1ERCC4KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451462-A | Method of treating inflammation and pain using heteramino benzofurans | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4426380-A | ANTIINFLAMMATORY, ANALGESIC, SUNSCREEN | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |