Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10947750 | 0.83 | HSP90AA1 (0.44) | HSP90AA1NR3C1CYP2C19L3MBTL1KMT2A | |
| SCHEMBL10950761 | 0.80 | HSP90AA1 (0.42) | HSP90AA1NR3C1TSHRKMT2ATSPO | |
| SCHEMBL5406966 | 0.78 | NR3C1 (0.42) | NR3C1CYP2C19L3MBTL1TSHRKMT2A | |
| SCHEMBL11062225 | 0.77 | ERCC1 (0.46) | HSP90AA1L3MBTL1TSHRKMT2AGAA | |
| Benzamide SCHEMBL10949386 | 0.76 | PTGS1 (0.43) | HSP90AA1NR3C1CYP2C19L3MBTL1TSHR | |
| SCHEMBL10949391 | 0.75 | PTGS1 (0.43) | HSP90AA1NR3C1CYP2C19L3MBTL1KMT2A | |
| SCHEMBL10780367 | 0.74 | CYP2C19 (0.40) | NR3C1CYP2C19L3MBTL1TSHRCRHR1 | |
| SCHEMBL22014041 | 0.72 | CYP2C19 (0.43) | NR3C1CYP2C19TSHRKMT2ACRHR1 | |
| SCHEMBL7002879 | 0.70 | CYP2C19 (0.49) | NR3C1CYP2C19TSHRCRHR1TSPO | |
| SCHEMBL12758969 | 0.70 | LMNA (0.35) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107620-A1 | Phenol derivatives | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | claimed |
| EP-0107620-A1 | Phenol derivatives | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | disclosed |