Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | KLK1 | P06870 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10947750 | 0.92 | HSP90AA1 (0.44) | PTGS1PTGS2HSP90AA1TRPM8POLB | |
| SCHEMBL10949391 | 0.88 | PTGS1 (0.43) | PTGS1PTGS2HSP90AA1CYP3A4CYP2C19 | |
| SCHEMBL10950761 | 0.81 | HSP90AA1 (0.42) | HSP90AA1TSHRMEN1KMT2ANR3C1 | |
| SCHEMBL11062225 | 0.79 | ERCC1 (0.46) | HSP90AA1CYP3A4MAPTTSHRL3MBTL1 | |
| SCHEMBL11041424 | 0.76 | HSP90AA1 (0.40) | HSP90AA1TRPM8TSHRCYP2C19L3MBTL1 | |
| SCHEMBL11168235 | 0.68 | TSHR (0.43) | HSP90AA1TSHRTDP1MEN1KMT2A | |
| SCHEMBL21963902 | 0.67 | TSPO (0.49) | TRPM8TSHRCYP2C19KMT2ANR3C1 | |
| SCHEMBL10780367 | 0.65 | CYP2C19 (0.40) | TRPM8TSHRCYP2C19L3MBTL1NR3C1 | |
| SCHEMBL28458480 | 0.64 | PTPN1 (0.65) | KLK1PLA2G10PLA2G2APOLBCYP3A4 | |
| SCHEMBL7002879 | 0.64 | CYP2C19 (0.49) | TRPM8TSHRCYP2C19NR3C1TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514415-A | ANALGESICS | CIBA GEIGY CORPORATION (US) | 1985-04-30 | — | — | US | disclosed |
| US-4451462-A | Method of treating inflammation and pain using heteramino benzofurans | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4426380-A | ANTIINFLAMMATORY, ANALGESIC, SUNSCREEN | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |