Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059620 | 0.87 | HTT (0.40) | GSK3BSMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL11059901 | 0.86 | DRD2 (0.40) | ALDH1A1MAPTKMT2AMEN1USP2 | |
| SCHEMBL11066556 | 0.86 | KDM4E (0.43) | GSK3BALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL11072295 | 0.86 | ALDH1A1 (0.44) | GSK3BSMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL11065300 | 0.84 | MMP2 (0.40) | SMN1; SMN2ALDH1A1HPGDHAO1NPSR1 | |
| SCHEMBL11059390 | 0.84 | ALDH1A1 (0.47) | GSK3BHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL11070637 | 0.74 | CYP1A2 (0.38) | ALDH1A1MAPTKDM4E | |
| SCHEMBL4262330 | 0.70 | GSK3B (0.43) | GSK3BSMN1; SMN2HDAC1HDAC3HDAC4 | |
| SCHEMBL11241053 | 0.69 | GABRP (0.30) | — | |
| SCHEMBL10938494 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425282-A | Preparation of 3-(arylvinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid esters and new intermediate therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-10 | — | — | US | disclosed |