Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059054 | 0.84 | — | — | |
| SCHEMBL11072295 | 0.79 | ALDH1A1 (0.44) | CYP1A2CYP2D6CYP2C19TSHRKDM4E | |
| SCHEMBL5796626 | 0.79 | PRKCA (0.33) | CYP2C9MAPT | |
| SCHEMBL16150048 | 0.76 | PRKCA (0.33) | — | |
| SCHEMBL11059620 | 0.75 | HTT (0.40) | HTTALDH1A1POLBMAPT | |
| SCHEMBL11059901 | 0.74 | DRD2 (0.40) | KDM4EALDH1A1MAPT | |
| SCHEMBL11062452 | 0.74 | GSK3B (0.40) | KDM4EALDH1A1MAPT | |
| SCHEMBL11019148 | 0.72 | MAOA (0.32) | — | |
| SCHEMBL10938494 | 0.72 | — | — | |
| SCHEMBL24840437 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425282-A | Preparation of 3-(arylvinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid esters and new intermediate therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-10 | — | — | US | disclosed |
| US-4400523-A | Process for the preparation of styryl-cyclopropanecarboxylic acid esters and new intermediate products for this process | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-23 | — | — | US | disclosed |
| EP-0018531-B1 | SUBSTITUTED 2,2-DIMETHYLPENTANE (ENE)-1-CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF STYRYL-CYCLOPROPANE-CARBOXYLATES | BAYER AG (DE) | 1983-01-26 | — | — | EP | disclosed |
| US-4325873-A | Process for the preparation of styryl-cyclopropanecarboxylic acid esters and intermediate products for this process | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-20 | — | — | US | disclosed |
| EP-0018531-A1 | Substituted 2,2-dimethylpentane (ene)-1-carboxylic acid derivatives, process for their preparation and their use for the preparation of styryl-cyclopropane-carboxylates | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |