Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065244 | 0.77 | BRD4 (0.47) | BRD4ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL9843278 | 0.69 | ADORA1 (0.51) | BRD4ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL10810899 | 0.68 | KDM4C (0.48) | BRD4ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL11062596 | 0.68 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10CASP1CASP7 | |
| SCHEMBL11062613 | 0.68 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10KDM4ERXFP1 | |
| SCHEMBL8224982 | 0.66 | HPGD (0.74) | ALDH1A1HPGDKDM4EMAPK1MEN1 | |
| SCHEMBL11220801 | 0.66 | ALDH1A1 (0.42) | BRD4ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL25970052 | 0.65 | MAT2A (0.41) | ALDH1A1HPGDHSD17B10KDM4EMAPK1 | |
| SCHEMBL822675 | 0.65 | L3MBTL1 (0.56) | BRD4ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL11715949 | 0.65 | ADORA1 (0.43) | ALDH1A1HPGDHSD17B10KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57024372-A | — | — | None | — | — | JP | disclosed |
| JP-S5724372-A | 5-OXO-2,5-DIHYDRO-1,2,4-TRIAZINE DERIVATIVE, ITS PREPARATION, AND HERBICIDE CONTAINING SAID COMPOUND AS ACTIVE COMPONENT | SUMITOMO CHEM CO LTD | 1982-02-08 | — | — | JP | disclosed |