Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10570121 | 0.86 | ABCB1 (0.51) | MEN1KMT2AATMUSP2HTT | |
| SCHEMBL11061136 | 0.84 | KCNH2 (0.56) | KCNH2ADRB2ADRB1ADRB3DRD4 | |
| SCHEMBL11068145 | 0.77 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL11066712 | 0.75 | DRD4 (0.55) | MEN1KMT2AATMADRB2ADRB1 | |
| SCHEMBL11064919 | 0.74 | ADRB2 (0.51) | KCNH2ADRB2ADRB1ADRB3SLC18A3 | |
| SCHEMBL11067546 | 0.74 | KCNH2 (0.52) | KCNH2ADRB2ADRB1ADRB3SLC18A3 | |
| SCHEMBL11070643 | 0.74 | KCNH2 (0.54) | KCNH2ADRB2ADRB1ADRB3SLC18A3 | |
| SCHEMBL11067472 | 0.74 | KCNH2 (0.54) | KCNH2ADRB2ADRB1ADRB3SLC18A3 | |
| SCHEMBL11065039 | 0.74 | DRD4 (0.60) | MEN1KMT2AATMADRB2ADRB1 | |
| SCHEMBL11067922 | 0.74 | KCNH2 (0.49) | KCNH2ADRB2ADRB1ADRB3SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |