Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10513959 | 0.89 | LMNA (0.32) | LMNAGAAHTT | |
| SCHEMBL11065956 | 0.87 | CYP1A2 (0.35) | LMNAGAAHTTPOLBALDH1A1 | |
| SCHEMBL11073898 | 0.85 | — | — | |
| SCHEMBL11069345 | 0.83 | GPR35 (0.33) | — | |
| SCHEMBL11071748 | 0.81 | IRAK4 (0.37) | LMNAGAAHTTPOLBALDH1A1 | |
| SCHEMBL11062722 | 0.81 | GABRA1 (0.34) | LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL11562794 | 0.79 | POLB (0.32) | POLB | |
| SCHEMBL11063432 | 0.78 | ALDH1A1 (0.34) | LMNAGAAHTTALDH1A1MAPT | |
| SCHEMBL11072576 | 0.76 | ACR (0.38) | LMNAHTTPOLBALDH1A1MAPT | |
| SCHEMBL11070756 | 0.75 | GAA (0.42) | LMNAGAAHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | claimed |
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |