Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.62 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11068513 | 0.99 | TBXAS1 (0.63) | TBXAS1LTA4HNAPRTKDM4E | |
| SCHEMBL5004504 | 0.84 | ALOX15 (0.70) | TBXAS1LTA4HALOX15 | |
| SCHEMBL11066918 | 0.82 | TSHR (0.65) | TBXAS1LTA4HTRPM8 | |
| SCHEMBL8853482 | 0.80 | TBXAS1 (0.59) | TBXAS1LTA4HNAPRT | |
| SCHEMBL11068319 | 0.80 | NAPRT (0.77) | TBXAS1NAPRT | |
| SCHEMBL2009003 | 0.79 | ALOX15 (0.62) | NAPRTALOX15 | |
| SCHEMBL9310930 | 0.79 | PLOD2 (0.50) | TBXAS1KDM4EALOX15 | |
| SCHEMBL10660572 | 0.79 | LTA4H (0.63) | TBXAS1LTA4H | |
| SCHEMBL15785422 | 0.79 | CYP3A4 (0.59) | ALOX15 | |
| Hydrochloric Acid SCHEMBL11059321 | 0.78 | NAPRT (0.74) | TBXAS1NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317828-A | ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | claimed |
| US-4427682-A | ANTICOAGULANTS, ANTIINFLAMMATORY, HYPOTENSIVE, OR ANTIALLERGEN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-01-24 | — | — | US | disclosed |
| US-4317828-A | ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | disclosed |
| US-4271170-A | THROMBOXANE SYNTHETASE ENZYME INHIBITOR USEFUL IN TREATING INFLAMMATION, HYPERTENSION, THROMBUS, CEREBRAL APOPLEXY, ASTHMA, AND CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD., (JP) | 1981-06-02 | — | — | US | disclosed |