Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7244253 | 0.75 | SIGMAR1 (0.45) | SIGMAR1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5163007 | 0.72 | POLB (0.44) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL12130607 | 0.70 | MEN1 (0.43) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9791933 | 0.70 | SIGMAR1 (0.50) | SIGMAR1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7250815 | 0.69 | SLC6A4 (0.71) | SIGMAR1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1389099 | 0.69 | CYP1A2 (0.41) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8971571 | 0.69 | TSHR (0.43) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10887167 | 0.68 | CYP1A2 (0.46) | SIGMAR1CYP1A2CYP2C19 | |
| SCHEMBL27650693 | 0.68 | SLC6A3 (0.53) | SIGMAR1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6186552 | 0.68 | CYP1A2 (0.46) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482573-A | Diphenylalkanoether and diphenylalkanone oximeether derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-13 | — | — | US | disclosed |