Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.52 |
| ▸ | NGFR | P08138 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065351 | 0.88 | GPR35 (0.39) | GPR35ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11069218 | 0.86 | KDM4E (0.48) | KDM4EMEN1ALDH1A1GLAGAA | |
| SCHEMBL11263377 | 0.85 | ALDH1A1 (0.45) | KDM4EMEN1ALDH1A1CYP1A2GAA | |
| SCHEMBL11261165 | 0.81 | GABRA1 (0.38) | GPR35KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL11075982 | 0.76 | KDM4E (0.46) | GPR35NGFRKDM4EMEN1GRIN2D | |
| SCHEMBL11065167 | 0.74 | GPR35 (0.64) | GPR35NGFRKDM4EMEN1GRIN2D | |
| SCHEMBL9452297 | 0.70 | GPR35 (0.54) | GPR35KDM4EMEN1GRIN2DGRIN3B | |
| SCHEMBL9452197 | 0.69 | GPR35 (0.50) | GPR35KDM4EMEN1GRIN2DGRIN3B | |
| SCHEMBL9452283 | 0.69 | HPGD (0.57) | GPR35KDM4EMEN1GRIN2DGRIN3B | |
| SCHEMBL9069080 | 0.69 | GPR35 (1.00) | GPR35NGFRKDM4EMEN1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062001-A2 | Acyl quinolinone derivatives, processes for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1982-10-06 | — | — | EP | claimed |
| US-4476132-A | Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them | CIBA-GEIGY CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |
| EP-0062001-A2 | Acyl quinolinone derivatives, processes for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1982-10-06 | — | — | EP | disclosed |