Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | HRH1 | P35367 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065708 | 0.78 | HTR5A (0.46) | DRD3DRD2HTR2AMC4RSIGMAR1 | |
| SCHEMBL11065888 | 0.76 | DRD2 (0.48) | DRD3DRD2SLC6A4SLC6A3HTR2A | |
| SCHEMBL11072794 | 0.74 | KCNH2 (0.42) | KCNH2HRH1LMNADRD3DRD2 | |
| SCHEMBL10766174 | 0.74 | BCHE (0.62) | KCNH2HRH1LMNADRD3DRD2 | |
| SCHEMBL12142396 | 0.73 | BCHE (0.55) | KCNH2HRH1LMNADRD3DRD2 | |
| SCHEMBL6966240 | 0.73 | HSP90AA1 (0.36) | KCNH2HRH1LMNADRD3SLC6A3 | |
| SCHEMBL21071819 | 0.72 | CARM1 (0.57) | DRD3DRD2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL19852050 | 0.72 | CARM1 (0.57) | DRD3DRD2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL19852044 | 0.72 | CARM1 (0.57) | DRD3DRD2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11070666 | 0.72 | SIGMAR1 (0.48) | DRD3DRD2SLC6A4SLC6A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |