Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 7/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065888 | 0.89 | DRD2 (0.48) | HTR5ADRD3DRD2SIGMAR1HTR2A | |
| SCHEMBL11069216 | 0.82 | CHRM2 (0.56) | DRD3DRD2HTR2A | |
| SCHEMBL11066510 | 0.81 | HTR2A (0.42) | MC4RDRD3DRD2SIGMAR1HTR2A | |
| SCHEMBL11070666 | 0.81 | SIGMAR1 (0.48) | DRD3DRD2SIGMAR1HTR2A | |
| SCHEMBL11072827 | 0.80 | SIGMAR1 (0.45) | DRD3DRD2SIGMAR1HTR2A | |
| SCHEMBL11064657 | 0.78 | KCNH2 (0.44) | MC4RDRD3DRD2SIGMAR1HTR2A | |
| SCHEMBL11362787 | 0.76 | HTR2A (0.55) | HTR5AMC4RDRD3DRD2SIGMAR1 | |
| SCHEMBL11360264 | 0.76 | SLC6A4 (0.53) | MC4RDRD3DRD2SIGMAR1 | |
| SCHEMBL10761329 | 0.74 | BCHE (0.64) | — | |
| SCHEMBL11067192 | 0.74 | NOS3 (0.45) | DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |