Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358816 | 0.84 | HTR2A (0.60) | SIGMAR1DRD2DRD3HTR2A | |
| SCHEMBL11065888 | 0.83 | DRD2 (0.48) | SIGMAR1DRD2DRD3SLC6A4HTR2A | |
| SCHEMBL11065708 | 0.81 | HTR5A (0.46) | SIGMAR1DRD2DRD3HTR2A | |
| SCHEMBL11072827 | 0.80 | SIGMAR1 (0.45) | SIGMAR1DRD2DRD3HTR2AKDM4E | |
| SCHEMBL11073339 | 0.80 | DRD2 (0.60) | DRD2DRD3HTR2ASLC6A2SLC6A3 | |
| SCHEMBL11066510 | 0.79 | HTR2A (0.42) | SIGMAR1DRD2DRD3HTR2A | |
| SCHEMBL11367314 | 0.79 | HTR2A (0.55) | HTR2AKDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL11065041 | 0.79 | DRD2 (0.59) | DRD2DRD3HTR2ASLC6A2SLC6A3 | |
| SCHEMBL8809168 | 0.79 | HTR2A (0.60) | DRD3SLC6A4HTR2ASLC6A2 | |
| SCHEMBL11561263 | 0.78 | HTR2A (0.53) | SIGMAR1DRD2DRD3SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |