Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 2/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063084 | 0.94 | MAPT (0.41) | MAPTRAF1MAP2K1MEN1KMT2A | |
| SCHEMBL11071318 | 0.81 | MAPT (0.41) | MAPTRAF1MAP2K1MEN1KMT2A | |
| SCHEMBL11068361 | 0.81 | DRD2 (0.45) | RAF1MAP2K1ADRB2ADRB1HTR1A | |
| SCHEMBL11066130 | 0.77 | PDE3B (0.53) | MAPT | |
| SCHEMBL11068094 | 0.77 | MAOA (0.50) | — | |
| SCHEMBL11067769 | 0.77 | PDE3B (0.51) | MAPTMEN1KMT2A | |
| SCHEMBL11069685 | 0.77 | ADRB2 (0.41) | ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL11068986 | 0.76 | PDE3B (0.51) | MAPT | |
| SCHEMBL11069157 | 0.76 | MAOA (0.51) | MAPTRAF1MAP2K1MEN1KMT2A | |
| SCHEMBL11062523 | 0.76 | PDE3B (0.49) | ADRB2ADRB1HTR1AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |