Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061677 | 0.82 | ADRB2 (0.41) | ADRB2ADRB1HTR1AOPRK1DRD2 | |
| SCHEMBL11287374 | 0.81 | MAPK1 (0.56) | ADRB2ADRB1HTR1AOPRK1DRD2 | |
| SCHEMBL11068361 | 0.79 | DRD2 (0.45) | ADRB2ADRB1HTR1AOPRK1DRD2 | |
| SCHEMBL11064570 | 0.77 | TRPM8 (0.43) | ADRB2ADRB1HTR1AOPRK1DRD2 | |
| SCHEMBL11065776 | 0.77 | ADRB2 (0.40) | ADRB2ADRB1HTR1AOPRK1DRD2 | |
| SCHEMBL11064862 | 0.77 | MAPT (0.43) | ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL11063084 | 0.76 | MAPT (0.41) | ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL11062524 | 0.76 | ADRB2 (0.41) | ADRB2ADRB1HTR1AOPRK1DRD2 | |
| SCHEMBL11065939 | 0.76 | TRPM8 (0.44) | ADRB2ADRB1HTR1AOPRK1DRD2 | |
| SCHEMBL11067557 | 0.75 | ADRB2 (0.39) | ADRB2ADRB1HTR1AOPRK1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |