Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 3/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11462428 | 0.82 | ALOX5 (0.39) | CNR2MRGPRX4PTGS1PTGS2PDE5A | |
| SCHEMBL11472173 | 0.81 | ALDH1A1 (0.47) | BRD4CNR2MRGPRX4KMT2AELANE | |
| SCHEMBL11064786 | 0.79 | POLB (0.36) | BRD4MRGPRX4KMT2APTGS1PTGS2 | |
| SCHEMBL11062094 | 0.78 | KCNH2 (0.38) | SLC15A1PTGS1ALDH1A1 | |
| SCHEMBL11471667 | 0.77 | MRGPRX4 (0.43) | BRD4CNR2MRGPRX4KMT2APTGS2 | |
| SCHEMBL11069825 | 0.75 | PDE5A (0.36) | BRD4MRGPRX4KMT2APDE5APDE1A | |
| SCHEMBL11069822 | 0.75 | PDE5A (0.36) | BRD4MRGPRX4KMT2APDE5APDE1A | |
| SCHEMBL11392950 | 0.75 | NOS3 (0.35) | BRD4CNR2KMT2APDE5APDE1A | |
| SCHEMBL11392948 | 0.75 | NOS3 (0.35) | BRD4CNR2KMT2APDE5APDE1A | |
| SCHEMBL11403555 | 0.75 | MRGPRX4 (0.42) | CNR2MRGPRX4PDE5APDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447613-A | Pyridyl esters and thiolesters of aminoalkanoic acids | ZOECON CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| US-4269981-A | Certain pyridylmethyl esters of formamido-lower-alkanoates and derivatives thereof | ZOECON CORPORATION (US) | 1981-05-26 | — | — | US | disclosed |
| US-4247701-A | Certain pesticidal substituted amino lower-alkanoates or lower-alkano-thioates containing pyridyl in the ester portion | ZOECON CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |