Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 8/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 2/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069822 | 1.00 | PDE5A (0.36) | PDE5APOLBBRD4PDE1APDE1B | |
| SCHEMBL11064786 | 0.84 | POLB (0.36) | PDE5APOLBBRD4PDE1APDE1B | |
| SCHEMBL11068255 | 0.82 | ADAMTS4 (0.37) | PDE5APOLBPDE1APDE1BPDE1C | |
| SCHEMBL11068260 | 0.82 | ADAMTS4 (0.37) | PDE5APOLBPDE1APDE1BPDE1C | |
| SCHEMBL11471667 | 0.78 | MRGPRX4 (0.43) | PDE5APOLBBRD4KDM4EL3MBTL1 | |
| SCHEMBL11064972 | 0.75 | BRD4 (0.39) | PDE5ABRD4PDE1APDE1BPDE1C | |
| SCHEMBL11068569 | 0.75 | ADAMTS4 (0.36) | PDE5APOLBPDE1APDE1BPDE1C | |
| SCHEMBL11472173 | 0.74 | ALDH1A1 (0.47) | PDE5ABRD4PDE1APDE1BPDE1C | |
| SCHEMBL11474142 | 0.72 | MAPT (0.51) | POLBALDH1A1HPGDMRGPRX4LMNA | |
| SCHEMBL11403558 | 0.71 | MRGPRX4 (0.42) | PDE5APDE1APDE1BPDE1CL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447613-A | Pyridyl esters and thiolesters of aminoalkanoic acids | ZOECON CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| US-4269981-A | Certain pyridylmethyl esters of formamido-lower-alkanoates and derivatives thereof | ZOECON CORPORATION (US) | 1981-05-26 | — | — | US | disclosed |
| US-4247701-A | Certain pesticidal substituted amino lower-alkanoates or lower-alkano-thioates containing pyridyl in the ester portion | ZOECON CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |