Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
| ▸ | TARS1 | P26639 | 1/20 | 0.37 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118998 | 0.89 | SCN9A (0.43) | P2RX3 | |
| SCHEMBL11071446 | 0.83 | ALDH1A1 (0.38) | KCNH2TRPV3P2RX3ALDH1A1HSD17B14 | |
| SCHEMBL11460618 | 0.82 | ALOX5 (0.40) | LMNAPTGS1 | |
| SCHEMBL11065707 | 0.82 | ADAMTS4 (0.39) | TRPV3P2RX3ALDH1A1ADAMTS4 | |
| SCHEMBL11167591 | 0.82 | P2RX3 (0.42) | P2RX3ALDH1A1LMNA | |
| SCHEMBL11275809 | 0.81 | ALDH1A1 (0.47) | KCNH2F2F10PRSS1PRSS2 | |
| SCHEMBL11478773 | 0.81 | ADAMTS4 (0.39) | TRPV3P2RX3ALDH1A1LMNAADAMTS4 | |
| SCHEMBL11066972 | 0.81 | ALDH1A1 (0.36) | KCNH2TRPV3P2RX3ALDH1A1HSD17B14 | |
| SCHEMBL11072017 | 0.80 | ADAMTS4 (0.38) | TRPV3P2RX3ALDH1A1OPRM1ADAMTS4 | |
| SCHEMBL11069125 | 0.79 | ADAMTS4 (0.38) | TRPV3P2RX3ALDH1A1LMNAADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447613-A | Pyridyl esters and thiolesters of aminoalkanoic acids | ZOECON CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| US-4269981-A | Certain pyridylmethyl esters of formamido-lower-alkanoates and derivatives thereof | ZOECON CORPORATION (US) | 1981-05-26 | — | — | US | disclosed |
| US-4247701-A | Certain pesticidal substituted amino lower-alkanoates or lower-alkano-thioates containing pyridyl in the ester portion | ZOECON CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |