Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073307 | 0.90 | MAOA (0.57) | MAOAMAOBSIGMAR1HTR1ADRD4 | |
| SCHEMBL11065044 | 0.89 | MAOA (0.61) | MAOAMAOBSIGMAR1DRD4MEN1 | |
| Hydrochloric Acid SCHEMBL11067443 | 0.88 | MAOA (0.60) | MAOAMAOBSIGMAR1DRD4MEN1 | |
| SCHEMBL11065083 | 0.88 | MAOA (0.65) | MAOAMAOBSIGMAR1DRD4MEN1 | |
| SCHEMBL11071304 | 0.85 | DRD4 (0.62) | MAOAMAOBGRIN1HTR1ADRD4 | |
| SCHEMBL11072939 | 0.85 | DRD4 (0.62) | DRD4SCN1ASCN5ASCN9AMEN1 | |
| SCHEMBL11063504 | 0.79 | KCNH2 (0.50) | MAOAMAOBDRD4MEN1KMT2A | |
| SCHEMBL11070311 | 0.77 | ADRB2 (0.44) | HTR1ADRD4SCN1ASCN5ASCN9A | |
| SCHEMBL18050048 | 0.76 | BRD4 (0.55) | MAOAMAOBHTR1ADRD4MEN1 | |
| Iodide SCHEMBL11068714 | 0.76 | DRD4 (0.42) | MAOAMAOBHTR1ADRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |