Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071279 | 0.79 | HDAC1 (0.41) | NPC1TSHRLMNAALOX15MAPK1 | |
| SCHEMBL11065352 | 0.74 | KMT2A (0.41) | NPC1TSHRALOX15MAPK1HSD17B10 | |
| SCHEMBL11287374 | 0.74 | MAPK1 (0.56) | TRPM8NPC1TSHRLMNAALOX15 | |
| SCHEMBL11067771 | 0.73 | PDE3B (0.41) | PDE3BPDE3ADRD2MEN1KMT2A | |
| SCHEMBL11071895 | 0.73 | PDE3B (0.40) | LMNAPDE3BPDE3AMEN1KMT2A | |
| SCHEMBL12090742 | 0.71 | CYP19A1 (0.48) | NPC1MAPK1HPGDDRD2MEN1 | |
| SCHEMBL11071318 | 0.71 | MAPT (0.41) | DRD2MEN1KMT2A | |
| SCHEMBL11278612 | 0.71 | LMNA (0.46) | NPC1LMNADRD2CCR1KCNH2 | |
| SCHEMBL11058886 | 0.71 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL11071361 | 0.71 | PDE3B (0.45) | SMN1; SMN2PDE3BPDE3ADRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |