Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 4/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6078617 | 0.83 | ADRA1A (0.43) | PDCD1CD274CASP6KDM4EL3MBTL1 | |
| SCHEMBL11065601 | 0.81 | ALDH1A1 (0.43) | PDCD1CD274S1PR1S1PR3EPHX1 | |
| SCHEMBL11066304 | 0.81 | PDCD1 (0.59) | PDCD1CD274S1PR1S1PR3CASP6 | |
| SCHEMBL6527857 | 0.78 | DCTPP1 (0.45) | ADRA1AADRA1BADRA1DCYP1A2DCTPP1 | |
| SCHEMBL30091380 | 0.78 | PDCD1 (0.69) | PDCD1CD274EPHX1CYP1A2 | |
| SCHEMBL11074941 | 0.78 | PDCD1 (0.69) | PDCD1CD274EPHX1CYP1A2 | |
| SCHEMBL16245269 | 0.75 | PDCD1 (0.76) | PDCD1CD274S1PR1S1PR3EPHX1 | |
| SCHEMBL18367730 | 0.75 | CD274 (0.70) | PDCD1CD274S1PR1S1PR3EPHX1 | |
| SCHEMBL21090970 | 0.74 | USP1 (0.38) | ADRA1AADRA1BADRA1DCYP1A2EDNRB | |
| SCHEMBL19980775 | 0.74 | DCTPP1 (0.48) | L3MBTL1ADRA1AADRA1BADRA1DNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426524-A | Heterocyclic substituted benzyl alcohol, insecticidal ester derivatives, and intermediates | FMC CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |