Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068121 | 0.86 | MMP1 (0.61) | MMP1MEN1KMT2ACYP3A4PDE4B | |
| SCHEMBL11068586 | 0.83 | ALDH1A1 (0.53) | MEN1KMT2ACYP3A4LMNAHDAC8 | |
| SCHEMBL11072396 | 0.82 | KMT2A (0.51) | MEN1KMT2ACYP3A4LMNANPC1 | |
| SCHEMBL27551854 | 0.82 | MMP1 (0.62) | MMP1MEN1KMT2ACYP3A4PDE4B | |
| SCHEMBL11067559 | 0.81 | SMN1; SMN2 (0.57) | MEN1KMT2ACYP3A4LMNANPC1 | |
| SCHEMBL16552644 | 0.79 | MMP1 (0.76) | MMP1MEN1KMT2APDE4BLMNA | |
| SCHEMBL11068248 | 0.79 | FPR2 (0.61) | MMP1MEN1KMT2ACYP3A4NPC1 | |
| SCHEMBL11072712 | 0.79 | HTT (0.52) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL9829827 | 0.79 | CA2 (0.58) | MEN1KMT2ACYP3A4NPC1RAB9A | |
| SCHEMBL5637591 | 0.79 | CA2 (0.58) | MEN1KMT2ACYP3A4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435329-A | ANTIHYPERTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-06 | — | — | US | disclosed |