Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065663 | 0.86 | MMP1 (0.64) | MMP1MEN1KMT2ACYP3A4PDE4B | |
| SCHEMBL11061055 | 0.84 | FNTA (0.53) | LMNAHDAC1POLBMAPTSMN1; SMN2 | |
| SCHEMBL11068039 | 0.83 | MAPK1 (0.53) | MEN1KMT2ACYP3A4LMNANPC1 | |
| SCHEMBL11068391 | 0.83 | SDCBP (0.64) | MMP1MEN1KMT2ANPSR1HDAC8 | |
| SCHEMBL11068495 | 0.82 | SMN1; SMN2 (0.54) | MMP1MEN1KMT2ACYP3A4LMNA | |
| SCHEMBL11063891 | 0.80 | MAPK1 (0.50) | MEN1KMT2ALMNARAB9ATP53 | |
| SCHEMBL16312234 | 0.80 | HTT (0.61) | MMP1LMNATHRBNPC1RAB9A | |
| SCHEMBL5838728 | 0.80 | NPSR1 (0.71) | MMP1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL7410707 | 0.80 | NPSR1 (0.71) | MMP1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL27551854 | 0.80 | MMP1 (0.62) | MMP1MEN1KMT2ACYP3A4PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435329-A | ANTIHYPERTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-06 | — | — | US | disclosed |