Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437097 | 0.76 | HSD11B1 (0.43) | SLC18A3HSD11B1NPSR1ALDH1A1 | |
| SCHEMBL8818649 | 0.76 | CARM1 (0.36) | ALDH1A1MAPTHSD17B10MBTD1L3MBTL3 | |
| SCHEMBL3429469 | 0.75 | USP30 (0.39) | SLC18A3HRH3NPSR1MAPTMBTD1 | |
| SCHEMBL20855371 | 0.72 | NPC1 (0.40) | HRH3HSD11B1ALDH1A1 | |
| SCHEMBL18751629 | 0.70 | SLC18A3 (0.51) | SLC18A3HRH3NPSR1ALDH1A1MCOLN3 | |
| SCHEMBL1989282 | 0.70 | SLC18A3 (0.51) | SLC18A3HRH3NPSR1ALDH1A1MCOLN3 | |
| SCHEMBL3879514 | 0.70 | HSD11B1 (0.54) | SLC18A3HSD11B1NPSR1ALDH1A1MCOLN3 | |
| Hydrochloric Acid SCHEMBL28558595 | 0.69 | SLC18A3 (0.50) | SLC18A3HRH3NPSR1CYP2D6CYP2C19 | |
| SCHEMBL5788854 | 0.69 | KMT2A (0.40) | SLC18A3HRH3NPSR1MAPTMBTD1 | |
| SCHEMBL9153287 | 0.68 | CHRNB2 (0.52) | SLC18A3HRH3NPSR1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468511-A | C-20- And C-23-Modified macrolide derivatives | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | disclosed |