Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10762987 | 0.77 | HTR1A (0.56) | HTR1AKCNH2NPC1EGFRLMNA | |
| SCHEMBL11070666 | 0.75 | SIGMAR1 (0.48) | CYP1A2GAADRD2SLC6A2HTR2A | |
| SCHEMBL11066536 | 0.74 | MEN1 (0.43) | MEN1KMT2AHTR1AMCHR1KCNH2 | |
| SCHEMBL11068654 | 0.73 | HTR1A (0.43) | MEN1KMT2AHTR1AMCHR1KCNH2 | |
| SCHEMBL11065888 | 0.73 | DRD2 (0.48) | CYP1A2GAADRD2HTR2ASLC6A4 | |
| SCHEMBL11065126 | 0.72 | DRD2 (0.58) | GAADRD2DRD3OPRK1 | |
| SCHEMBL9076669 | 0.72 | KCNH2 (0.78) | MEN1KMT2AHTR1AKCNH2NPC1 | |
| SCHEMBL18590353 | 0.72 | KCNH2 (0.78) | MEN1KMT2AHTR1AKCNH2NPC1 | |
| SCHEMBL11358468 | 0.71 | GRIN2B (0.53) | MEN1KMT2AHTR1AMCHR1GRIN2D | |
| SCHEMBL11065708 | 0.71 | HTR5A (0.46) | DRD2HTR2AMC4RDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |