Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL10686325 | 0.89 | TBXAS1 (0.41) | TBXAS1ALDH1A1TP53POLBTDP1 | |
| SCHEMBL8807237 | 0.84 | TBXAS1 (0.65) | TBXAS1ALDH1A1 | |
| Ethylene SCHEMBL10683429 | 0.81 | CYP11B1 (0.46) | ALDH1A1NPSR1CHRNB2CHRNA4 | |
| Ethylene SCHEMBL10685834 | 0.79 | TDP1 (0.39) | TBXAS1ALDH1A1TP53POLBTDP1 | |
| SCHEMBL11068717 | 0.79 | SMN1; SMN2 (0.49) | TBXAS1ALDH1A1GRM2 | |
| SCHEMBL11062743 | 0.77 | KCNA5 (0.41) | ALDH1A1TDP1 | |
| 4-Formylpyridine SCHEMBL2639850 | 0.77 | LMNA (0.43) | ALDH1A1NPSR1 | |
| SCHEMBL11066568 | 0.76 | TBXAS1 (0.49) | TBXAS1ALDH1A1TP53POLBTDP1 | |
| Ethylene SCHEMBL6226363 | 0.75 | LMNA (0.48) | ALDH1A1 | |
| Ethylene SCHEMBL10685172 | 0.74 | ALOX5 (0.44) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4427682-A | ANTICOAGULANTS, ANTIINFLAMMATORY, HYPOTENSIVE, OR ANTIALLERGEN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-01-24 | — | — | US | disclosed |
| US-4317828-A | ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | disclosed |
| US-4271170-A | THROMBOXANE SYNTHETASE ENZYME INHIBITOR USEFUL IN TREATING INFLAMMATION, HYPERTENSION, THROMBUS, CEREBRAL APOPLEXY, ASTHMA, AND CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD., (JP) | 1981-06-02 | — | — | US | disclosed |