Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066566 | 0.89 | TBXAS1 (0.52) | TBXAS1TDP1ALDH1A1TP53POLB | |
| Ethylene SCHEMBL10685834 | 0.88 | TDP1 (0.39) | TBXAS1TDP1L3MBTL1ALDH1A1TP53 | |
| SCHEMBL10681531 | 0.83 | CHRNA7 (0.52) | TBXAS1TDP1L3MBTL1 | |
| Ethylene SCHEMBL10683429 | 0.82 | CYP11B1 (0.46) | ALDH1A1NPSR1 | |
| Ethylene SCHEMBL10688858 | 0.82 | HTR1A (0.40) | TBXAS1TDP1L3MBTL1ALDH1A1TP53 | |
| Ethylene SCHEMBL6226363 | 0.78 | LMNA (0.48) | ALDH1A1 | |
| SCHEMBL3126539 | 0.77 | ALDH1A1 (0.41) | ALDH1A1NPSR1 | |
| Ethylene SCHEMBL10685172 | 0.77 | ALOX5 (0.44) | — | |
| SCHEMBL11068717 | 0.76 | SMN1; SMN2 (0.49) | TBXAS1L3MBTL1ALDH1A1 | |
| Ethylene SCHEMBL10689209 | 0.74 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745120-A | CARDIOYASCULAR DISORDERS, ANTICOAGULANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-17 | — | — | US | disclosed |