Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081735 | 0.84 | KDM4E (0.52) | ABCB11KDM4EALDH1A1GAAGLA | |
| SCHEMBL11071263 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1TSHRGAAGLA | |
| SCHEMBL11066769 | 0.81 | ABCB11 (0.49) | ABCB11KDM4EALDH1A1TSHRGAA | |
| SCHEMBL11098611 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1TSHRGAAGLA | |
| SCHEMBL10038067 | 0.72 | NFKB1 (0.56) | KDM4EALDH1A1TSHRGAAGLA | |
| SCHEMBL11075853 | 0.70 | KDM4E (0.49) | KDM4EALDH1A1TSHRGAAGLA | |
| SCHEMBL11110116 | 0.70 | ABCB11 (0.43) | ABCB11MAPTHPGDPOLBTDP1 | |
| SCHEMBL11071974 | 0.69 | KDM4E (0.57) | KDM4EALDH1A1TSHRGAAGLA | |
| Probicromil SCHEMBL371493 | 0.68 | PDE5A (0.55) | ABCB11KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11081738 | 0.68 | KDM4E (0.49) | KDM4EALDH1A1GAAGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | claimed |