Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155682 | 0.80 | TSHR (0.57) | ALDH1A1L3MBTL1TP53LMNAMAPT | |
| SCHEMBL11301916 | 0.78 | AURKA (0.40) | ALDH1A1TP53MAPTCYP2C19TSHR | |
| SCHEMBL11067487 | 0.76 | SMN1; SMN2 (0.41) | ALDH1A1LMNAMAPTKDM4ECYP1A2 | |
| SCHEMBL28409108 | 0.75 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1TP53LMNAMAPT | |
| SCHEMBL2510669 | 0.74 | MAPT (0.48) | ALDH1A1L3MBTL1TP53LMNAMAPT | |
| SCHEMBL11163042 | 0.73 | TSHR (0.46) | ALDH1A1TP53LMNAHPGDTSHR | |
| SCHEMBL11062628 | 0.73 | KDM4E (0.62) | ALDH1A1L3MBTL1LMNAMAPTKDM4E | |
| SCHEMBL5180569 | 0.73 | GAA (0.48) | ALDH1A1L3MBTL1TP53LMNAMAPT | |
| SCHEMBL11299103 | 0.72 | NLRP3 (0.39) | ALDH1A1L3MBTL1TP53LMNAMAPT | |
| SCHEMBL11788534 | 0.72 | CDC25B (0.57) | ALDH1A1L3MBTL1KDM4EHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |