Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5745582 | 0.98 | MAPT (0.53) | MAPTGAAMAPK1TSHRHTT | |
| Nitric Acid SCHEMBL27764480 | 0.86 | ALDH1A1 (0.47) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL11695156 | 0.84 | ALDH1A1 (0.53) | TSHRALDH1A1CYP19A1KDM1ATDP1 | |
| SCHEMBL76201 | 0.82 | ALDH1A1 (0.52) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL16659206 | 0.81 | SMN1; SMN2 (0.56) | MAPTGAAMAPK1TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL27868120 | 0.80 | MAPT (0.53) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL29287691 | 0.79 | KIT (0.52) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL30898567 | 0.79 | ALDH1A1 (0.58) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL77823 | 0.78 | KDM4E (0.67) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL2438047 | 0.78 | KDM4E (0.67) | MAPTGAAMAPK1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 804 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584261-A1 | MODULATORS OF ALPHA-1 ANTITRYPSIN | Vertex Pharmaceuticals Incorporated (US) | 2025-07-16 | — | — | EP | claimed |
| CN-120166990-A | Alpha-1 antitrypsin modulators | 弗特克斯药品有限公司 | 2025-06-17 | — | — | CN | claimed |
| US-20240158404-A1 | MODULATORS OF ALPHA-1 ANTITRYPSIN | VERTEX PHARMACEUTICALS INCORPORATED | 2024-05-16 | — | — | US | claimed |
| WO-2024054624-A1 | MODULATORS OF ALPHA-1 ANTITRYPSIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-03-14 | — | — | WO | claimed |
| US-10696611-B2 | Adamantane derivative compound | AMOREPACIFIC CORPORATION (KR) | 2020-06-30 | — | — | US | claimed |
| EP-1773768-B1 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2018-08-22 | — | — | EP | claimed |
| US-20170283347-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | AMOREPACIFIC CORPORATION (KR) | 2017-10-05 | — | — | US | claimed |
| EP-3187486-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | Amorepacific Corporation (KR) | 2017-07-05 | — | — | EP | claimed |
| US-8288552-B2 | Dihydropyridone amidesas P2X7 modulators | ROCHE PALO ALTO LLC (US) | 2012-10-16 | — | — | US | claimed |
| CN-101450906-A | Method for preparing 3-amino-4-fluorophenol | TAIXING KANGPENG CHEMICALS CO (CN) | 2009-06-10 | — | — | CN | claimed |
| EP-1773768-A4 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2008-08-06 | — | — | EP | claimed |
| EP-1773768-A2 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | Exelixis, Inc. (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2006012642-A2 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS, INC. (US) | 2006-02-02 | — | — | WO | claimed |
| EP-4747241-A1 | BENZIMIDAZOLE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| CN-122036709-A | Halogenated anisole-containing side chain dithienyl pyrrole monomer, conjugated polymer, preparation method and application | 南阳师范学院 | 2026-05-15 | — | — | CN | disclosed |
| EP-4695248-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2026-02-18 | — | — | EP | disclosed |
| US-4593037-A | Compound substituted with phenyl rings | PFIZER INC. (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0175452-A1 | 1,3-Disubstituted piperidine compounds as neuroleptic agents | PFIZER INC. (US) | 1986-03-26 | — | — | EP | disclosed |
| US-4145364-A | PREPARATION OF FLUORINATED ANILINES | MERCK & CO., INC. (US) | 1979-03-20 | — | — | US | disclosed |
| US-4044049-A | Phenyl benzoic acid compounds | MERCK & CO., INC. (US) | 1977-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696611-B2 | Adamantane derivative compound | ADAM8, BACE1, CYP17A1 | MAPT 1527/4885GAA 743/4885MAPK1 2937/4885 |
| US-20170283347-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | ADAM8, CYP17A1, ADAM10 | MAPT 1766/4885GAA 1163/4885MAPK1 2795/4885 |
| US-20240158404-A1 | MODULATORS OF ALPHA-1 ANTITRYPSIN | SERPINA2, SERPINA3, SERPINB1 | MAPT 1912/4885GAA 142/4885MAPK1 2125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.