Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SDCBP | O00560 | 3/20 | 0.51 |
| ▸ | SDC2 | P34741 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061055 | 0.91 | FNTA (0.53) | SMN1; SMN2LMNAHPGDL3MBTL1MAPT | |
| SCHEMBL11067559 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9AFFAR1LMNACYP1A2 | |
| SCHEMBL11068039 | 0.84 | MAPK1 (0.53) | RAB9ALMNACYP1A2HPGDKMT2A | |
| SCHEMBL11068391 | 0.84 | SDCBP (0.64) | KMT2AMEN1SDCBPSDC2FNTA | |
| Biphenyl SCHEMBL27677177 | 0.82 | FNTA (0.53) | SMN1; SMN2RAB9ALMNAHPGDL3MBTL1 | |
| SCHEMBL11068121 | 0.82 | MMP1 (0.61) | SMN1; SMN2RAB9ALMNAKMT2AMAPT | |
| Biphenyl SCHEMBL27698554 | 0.80 | FNTA (0.51) | SMN1; SMN2LMNAHPGDSDCBPSDC2 | |
| SCHEMBL4760256 | 0.79 | DGAT1 (0.62) | RAB9ALMNAGAAMMP2MMP3 | |
| SCHEMBL1750357 | 0.79 | DGAT1 (0.62) | RAB9ALMNAGAAMMP2MMP3 | |
| SCHEMBL7361586 | 0.78 | ALDH1A1 (0.67) | SMN1; SMN2LMNAHPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435329-A | ANTIHYPERTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-06 | — | — | US | disclosed |