Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27640914 | 0.74 | PKM (0.47) | SMN1; SMN2TSHRHTR6HTTCA1 | |
| SCHEMBL7266697 | 0.69 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRHTR6HTTCA1 | |
| SCHEMBL3828442 | 0.69 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRHTR6HTTCA1 | |
| SCHEMBL9826055 | 0.69 | HTR6 (0.46) | SMN1; SMN2TSHRHTR6CA1CA2 | |
| Potassium SCHEMBL31612541 | 0.68 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRHTR6HTTCA1 | |
| SCHEMBL13924742 | 0.67 | CA2 (0.44) | SMN1; SMN2TSHRCA1CA2ALDH1A1 | |
| SCHEMBL3245447 | 0.66 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRHTR6HTTCA1 | |
| SCHEMBL28235593 | 0.66 | HTT (0.53) | SMN1; SMN2TSHRHTR6HTTCA1 | |
| SCHEMBL1526740 | 0.66 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRHTR6HTTCA1 | |
| SCHEMBL10599045 | 0.65 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRHTR6HTTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451279-A | SAFENERS | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4449999-A | PLANT SAFENING AGENTS; PROTECTIVE COATINGS FOR SEEDS | CIBA-GEIGY CORPORATION (US) | 1984-05-22 | — | — | US | disclosed |
| US-4425151-A | Sulfur-containing oxime compounds, processes for producing them, and their use for protecting cultivated plants | CIBA-GEIGY CORPORATION (US) | 1984-01-10 | — | — | US | disclosed |
| US-4394152-A | Sulfur-containing oxime compounds for protecting cultivated plants | CIBA-GEIGY CORPORATION (US) | 1983-07-19 | — | — | US | disclosed |
| US-4382893-A | PLANT SAFTENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-05-10 | — | — | US | disclosed |
| US-4278613-A | ANTIDOTES | CIBA-GEIGY CORPORATION (US) | 1981-07-14 | — | — | US | disclosed |